Biotechnology & Health Technologies

Nuclear Medicine & Radioisotope Technologies

The capacity to produce and apply medical radioisotopes and radiation technologies, isotope supply, radiopharmaceuticals, and the therapy and imaging systems that depend on a fragile global chain.

Capability group
Biotechnology & Health Technologies
Domain
Critical Technology · Hard Power
Identifier
factbase.org/cap/JH8DZ65Q2E
Reference
Nuclear medicine Wikipedia

Papers

33.4k

2020–2024

Paper growth

+6%

2020–24 on 2015–19

Patent families

14.5k

2020–2024

Filed abroad

45%

families in more than one office

In the framework

What the capability covers and what it leaves to others, and the indicators it will be measured by.

Bounds

Covers radioisotope and radiation-medicine technology; research reactors and processing facilities belong to Strategic Infrastructure, clinical delivery to Human Capital's health system, and supply concentration is the control-layer read that justifies the node.

Lineage

Carried from v0.0 (formerly Nuclear medicine and radiation therapy) with the same identifier; retained as a standalone capability on supply-chain logic, a global dependence on few producers, rather than on research-field logic.

Indicators

  • medical isotope production sharePending
  • research reactors producing isotopesPending
  • radiopharmaceutical approvalsPending

Research

Papers classified to the capability, by year and by the nation of their authors' institutions, 2020–2024. Read from the v0.0 research topic Nuclear medicine and radiation therapy.

Papers by year

The five leading nations, papers by year

Share of papers, 2020–2024

Of papers with a known author nation; 32% have none and are left out.

  1. 1United States20.5%6,154 papers
  2. 2Germany7.5%2,234 papers
  3. 3China7.4%2,202 papers
  4. 4Italy4.9%1,468 papers
  5. 5United Kingdom4.7%1,403 papers
  6. 6Japan4.4%1,333 papers
  7. 7Canada3.9%1,171 papers
  8. 8France3.3%980 papers
  9. 9Netherlands3.2%967 papers
  10. 10India3.2%952 papers

Leading institutions, 2020–2024

By fractional count: each paper divided among its authors' institutions.

  1. 1Memorial Sloan Kettering Cancer Center196fractional papers
  2. 2The University of Texas MD Anderson Cancer Center169fractional papers
  3. 3University of California, Los Angeles130fractional papers
  4. 4University of California, San Francisco91fractional papers
  5. 5Johns Hopkins University90fractional papers
  6. 6Chinese Academy of Medical Sciences & Peking Union Medical College88fractional papers
  7. 7Stanford University87fractional papers
  8. 8Cornell University83fractional papers
  9. 9Washington University in St. Louis78fractional papers
  10. 10Peking University67fractional papers

Patents

Patent families by the nation of origin of their applicants and their earliest priority year, from the CPC and IPC classes the capability is read from. 2025 onwards is incomplete: families are published 18 months after priority.

Families by priority year

The five leading origins, families by year

10,674 applicants filed here in 2015–2024; the five largest held 5% of families (HHI 13 of 10,000: unconcentrated).

Share of families by origin, 2020–2024

  1. 1China51.4%7,448 families
  2. 2United States18.1%2,625 families
  3. 3Japan7.6%1,097 families
  4. 4South Korea6.1%878 families
  5. 5Germany3.1%447 families
  6. 6Switzerland2.4%345 families
  7. 7United Kingdom1.5%216 families
  8. 8Canada1.5%211 families
  9. 9France1.1%155 families
  10. 10Netherlands0.9%134 families

Applicants filing most internationally, 2015–2024

Families filed in more than one office, by applicant as the offices name them.

  1. 1KONINKLIJKE PHILIPS NV318international families
  2. 2SHANGHAI UNITED IMAGING HEALTHCARE CO LTD297international families
  3. 3SIEMENS HEALTHINEERS INT AG213international families
  4. 4SIEMENS HEALTHCARE GMBH186international families
  5. 5HITACHI LTD184international families
  6. 6Elekta ltd174international families
  7. 7CANON MEDICAL SYSTEMS CORP162international families
  8. 8UNIV CALIFORNIA152international families
  9. 9OUR UNITED CORP150international families
  10. 10VARIAN MED SYS INC128international families

Classification read

  • A61K51/00 Radiopharmaceuticals · 167.5k documents
  • G21G Radioisotope production and radioactive sources · 27.4k documents
  • H05H6/00 Targets for producing isotopes by nuclear reaction · 3.9k documents
  • H05H13/00 Cyclotrons · 5.9k documents
  • C07B59/00 Isotope-labelled organic compounds · 36.1k documents
  • A61N5/10 Radiotherapy: X-ray, gamma, particle beams, brachytherapy · 253.4k documents
  • G01T1/161 Radiation detection for nuclear medicine · 20.4k documents
  • A61B6/037 Emission tomography (PET, SPECT) · 24.1k documents

Shares inventions with

Capabilities whose classes the same families also fall in, by overlap (Jaccard).

Companies

50 companies in this capability, across 8 regions. The leading 12:

  1. 1Siemens HealthineersLeading maker of SPECT and PET/CT scanners (Biograph line) and, through PETNET Solutions, one of the largest PET radiopharmaceutical manufacturing and distribution networks; also owns Varian radiotherapy.Manufacture
  2. 2GE HealthCareMajor supplier of PET/CT, SPECT/CT and cyclotrons plus a Pharmaceutical Diagnostics unit making SPECT and PET tracers (e.g. DaTscan, Vizamyl) and owner of the MIM Software molecular-imaging suite.Manufacture
  3. 3NovartisGlobal leader in radioligand therapy with Lutathera and Pluvicto (Lu-177), produced by its Advanced Accelerator Applications unit across dedicated radiopharmaceutical plants.Design
  4. 4CuriumOne of the world's largest nuclear medicine companies, a top supplier of Mo-99/Tc-99m generators, I-131 and SPECT/PET radiopharmaceuticals, formed from Mallinckrodt Nuclear Medicine and IBA Molecular.Manufacture
  5. 5Lantheus HoldingsMarkets the leading PSMA PET agent Pylarify, TechneLite Tc-99m generators and cardiac imaging agents, and is building a radiotherapeutics pipeline.Manufacture
  6. 6Cardinal HealthOperates the largest US network of nuclear pharmacies and cyclotron PET facilities through its Nuclear and Precision Health Solutions business, dispensing unit-dose radiopharmaceuticals.Operation
  7. 7RosatomRussian state nuclear corporation whose subsidiaries (JSC Isotope, Rusatom Healthcare, research reactors) are major exporters of Mo-99, Lu-177, Co-60, I-131 and other medical isotopes.Manufacture
  8. 8NRG|PALLASOperates the High Flux Reactor at Petten, historically a supplier of a large share of the world's Mo-99 and Lu-177 targets, and is building the PALLAS replacement isotope reactor.Operation
  9. 9Institute for Radioelements (IRE)One of the few global processors of irradiated uranium targets into Mo-99, supplying a significant share of world demand, and a producer of therapeutic isotopes.Manufacture
  10. 10NTP RadioisotopesSubsidiary of South Africa's Necsa that processes Mo-99 from the SAFARI-1 reactor and is one of the world's major Mo-99 and I-131 suppliers, exporting to over 60 countries.Manufacture
  11. 11ANSTOAustralia's nuclear agency, operating the OPAL reactor and ANSTO Nuclear Medicine Mo-99 plant that supply Tc-99m generators domestically and for export.Manufacture
  12. 12BWX TechnologiesIts BWXT Medical unit (Ottawa, acquired from Nordion) produces I-125, Y-90 and other isotopes and has developed a non-HEU Mo-99/Tc-99m generator.Manufacture
All 50 in the Companies table →