Biotechnology & Health Technologies

Genomics & Biological Data

The capacity to read and hold biology at national scale: sequencing, genomic analysis and the biological datasets that are becoming strategic assets in their own right.

Capability group
Biotechnology & Health Technologies
Domain
Critical Technology · Hard Power
Identifier
factbase.org/cap/SR9QT9QP16
Reference
DNA sequencing Wikipedia

Papers

14.9k

2020–2024

Paper growth

+20%

2020–24 on 2015–19

Patent families

87.9k

2020–2024

Filed abroad

25%

families in more than one office

In the framework

What the capability covers and what it leaves to others, and the indicators it will be measured by.

Bounds

Covers sequencing and biological-data capacity; population health data governance belongs to the governance domain, health outcomes to Human Capital, and data-holding concentration reads at the control layer.

Lineage

Carried from v0.0 (formerly Genomic sequencing and analysis) with the same identifier; biological data named as strategic asset, the shift from technique to capacity.

Indicators

  • research publication share in genomicsResearch
  • national sequencing capacityPending
  • population genomic datasets heldPending

Research

Papers classified to the capability, by year and by the nation of their authors' institutions, 2020–2024. Read from the v0.0 research topic Genomic sequencing and analysis.

Papers by year

The five leading nations, papers by year

Share of papers, 2020–2024

Of papers with a known author nation; 27% have none and are left out.

  1. 1China20.5%3,060 papers
  2. 2United States18.3%2,740 papers
  3. 3United Kingdom5.6%838 papers
  4. 4India4.4%665 papers
  5. 5Australia3.1%459 papers
  6. 6Germany2.8%413 papers
  7. 7Italy2.6%395 papers
  8. 8France2.6%387 papers
  9. 9Canada2.6%384 papers
  10. 10Spain2.3%345 papers

Leading institutions, 2020–2024

By fractional count: each paper divided among its authors' institutions.

  1. 1Chinese Academy of Agricultural Sciences41fractional papers
  2. 2Sun Yat-sen University41fractional papers
  3. 3Sichuan University38fractional papers
  4. 4Chinese Academy of Sciences34fractional papers
  5. 5Zhejiang University34fractional papers
  6. 6Peking University31fractional papers
  7. 7Chinese Academy of Medical Sciences & Peking Union Medical College31fractional papers
  8. 8Shanghai Jiao Tong University29fractional papers
  9. 9Central South University27fractional papers
  10. 10Fudan University21fractional papers

Patents

Patent families by the nation of origin of their applicants and their earliest priority year, from the CPC and IPC classes the capability is read from. 2025 onwards is incomplete: families are published 18 months after priority.

Families by priority year

The five leading origins, families by year

28,020 applicants filed here in 2015–2024; the five largest held 4% of families (HHI 7 of 10,000: unconcentrated).

Share of families by origin, 2020–2024

  1. 1China69.6%61,132 families
  2. 2United States13.2%11,638 families
  3. 3South Korea6.6%5,786 families
  4. 4Japan2.7%2,414 families
  5. 5Germany1.0%912 families
  6. 6United Kingdom0.9%759 families
  7. 7France0.6%563 families
  8. 8Switzerland0.5%429 families
  9. 9Taiwan0.5%403 families
  10. 10Netherlands0.4%358 families

Applicants filing most internationally, 2015–2024

Families filed in more than one office, by applicant as the offices name them.

  1. 1ILLUMINA INC784international families
  2. 2UNIV CALIFORNIA647international families
  3. 3PIONEER HI BRED INT495international families
  4. 4HOFFMANN LA ROCHE482international families
  5. 5INST NAT SANTE RECH MED351international families
  6. 6UNIV LELAND STANFORD JUNIOR318international families
  7. 7ROCHE DIAGNOSTICS GMBH309international families
  8. 8HARVARD COLLEGE297international families
  9. 9MASSACHUSETTS INST TECHNOLOGY294international families
  10. 1010X GENOMICS INC281international families

Classification read

  • C12Q1/68 Nucleic acid analysis: sequencing, amplification, probes · 1.1m documents
  • G16B Bioinformatics and genomic data processing · 388.3k documents

Shares inventions with

Capabilities whose classes the same families also fall in, by overlap (Jaccard).

Companies

50 companies in this capability, across 8 regions. The leading 12:

  1. 1IlluminaDominant supplier of short-read sequencing-by-synthesis instruments (NovaSeq X, NextSeq, MiSeq) and the top international patent applicant in this capability.Manufacture
  2. 2Thermo Fisher ScientificMakes Applied Biosystems capillary (Sanger) sequencers, Ion Torrent semiconductor NGS, and a large share of the world's genomics reagents and sample-prep consumables.Equipment & materials
  3. 3BGI GroupChina's genomics champion; its affiliate MGI Tech (SSE 688114) makes DNBSEQ sequencers that compete with Illumina, and BGI Genomics (SZSE 300676) is one of the world's largest sequencing service providers.Manufacture
  4. 4Oxford Nanopore TechnologiesDeveloper of nanopore long-read, real-time sequencers (MinION, GridION, PromethION) used from field surveillance to population genomics.Manufacture
  5. 5Pacific BiosciencesMaker of HiFi long-read SMRT sequencers (Revio, Vega) and the Onso short-read system, widely used for reference genomes and population programmes.Manufacture
  6. 6RocheMajor genomics patent holder supplying KAPA library-prep and target-enrichment chemistry and developing its Sequencing by Expansion (SBX) NGS platform.Equipment & materials
  7. 7Agilent TechnologiesSupplies SureSelect target enrichment, oligo pools, TapeStation/Bioanalyzer QC instruments and genomic analysis software used across sequencing workflows.Equipment & materials
  8. 8Danaher (Cytiva, Pall)Owns Integrated DNA Technologies (oligos and NGS panels), Beckman Coulter Life Sciences (genomic sample-prep automation) and Aldevron (plasmid DNA).Equipment & materials
  9. 910x GenomicsLeader in single-cell (Chromium) and spatial (Visium, Xenium) genomics platforms and one of the top international patent applicants in the field.Equipment & materials
  10. 10QiagenGlobal leader in nucleic-acid sample preparation, NGS panels and bioinformatics/knowledge bases (QIAGEN Digital Insights, CLC, HGMD).Equipment & materials
  11. 11Regeneron PharmaceuticalsIts Regeneron Genetics Center has sequenced exomes of more than two million people, including UK Biobank, making it one of the largest holders of linked human genetic data.Operation
  12. 12Element BiosciencesVenture-backed maker of the AVITI benchtop sequencer using avidity sequencing chemistry, a leading new challenger in short-read NGS.Manufacture
All 50 in the Companies table →